from the University of Virginia. Carvedilol is a type of medication known as a “beta-blocker”, which relaxes the muscle cells in the heart and blood vessels to lower blood pressure. Unfortunately, some commonly used drugs can cause pain, even the ones available without a prescription. © 2020 Remedy Health Media, LLC ALL RIGHTS RESERVED, https://www.healthcentral.com/article/top-5-drugs-that-can-cause-pain, OTC anti-inflammatory medication can also cause pain, nerve damage in the form of peripheral neuropathy, revent the neuropathy from occurring in the first place by taking Acetyl-L-Carnitine (1000 mg three times daily), Muscle pain and weakness is well known to be a resulting side-effect from cholesterol-lowering drugs, standard for trustworthy health information, Caffeine-containing medications (including Excedrin, Midol, Anacin): If you are experiencing headaches and you are also using a caffeine-containing medication more than two or three times per week, your headaches might be caused by these over-the-counter (OTC) medications. Depending upon the cause, muscle pain can be mild or severe and debilitating. Antibiotics typically refers to drugs that treat bacterial infections, and antivirals are medications that treat viral infections. This cycle causes a frequent roller coaster of up's and down's that sensitizes the nervous system to the point that you feel more pain. Being aware of the danger that some of the medications you are using might also be causing your pain is an important step towards potentially getting off that ride. Supplementing with magnesium can also help muscle cramps. This site complies with the HONcode standard for trustworthy health information. On rare occasions, statin drugs break down muscle cells, releasing a protein enzyme called creatine phosphokinase (CPK). It is also known to potentially cause problems such as diarrhea, constipation, headache, fatigue and muscle wasting. A herniated disk is a common cause of lower back and leg pain. Blunt force trauma caused by a strong impact to the body. electrolyte imbalances, such as hypokalemia (potassium deficiency), hypomagnesemia (magnesium deficiency), and hypercalcemia (elevated calcium in … He is a pathologist and has experience in internal medicine and cancer research. Gemfibrozil is another. Muscle pain and weakness is well known to be a resulting side-effect from cholesterol-lowering drugs, but can easily be mistaken for other things like fibromyalgia without anyone realizing that a drug is causing the pain. The risk of very serious side effects is extremely low, and calculated in … Impaired Muscle Control and Balance Benzodiazepines and antipsychotics such as olanzapine and quetiapine can impair muscle control and coordination, explains MayoClinic.com. Myalgia also often comes with mild feelings of weakness. Colchicine is one such drug. Immune scavenger cells (green) crowd around muscle fibers (red), damaging them and causing muscle pain and weakness. The cause of your pain might be easy to figure out, especially if you experienced a traumatic injury or recently exercised at the health club. Not only do you feel more pain, you feel anxious, restless and have trouble sleeping. Muscle problems have many possible causes. However, observational studies have shown that at least 10% to 15% of statin users complain of muscle pain [6][40]. Myalgia:This type of muscle pain usually feels like mild soreness in the shoulders, arms, hips or thighs. These include some recreational drugs, antibiotics, chemotherapy drugs, drugs affecting the hormonal system, drugs for cholesterol as well as heart and stomach drugs. Upper arm muscle pain can substantially affect your day-to-day activities. Antivirals such as zidovudine and lamivudine used to treat HIV are offenders, as are antiparasitics such as chloroquine used to treat malaria. A previously unknown autoimmune muscle disease involving sudden onset of debilitating muscle pain and weakness has been identified. Copyright © 2020 Leaf Group Ltd., all rights reserved. Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. Too much cholesterol in the blood can cause a buildup of plaque on the walls of the arteries. Corticosteriods are known to weaken tendon and lead to rupture, and corticosteroids are knwn as something NOT to be given with fluoroquinolone (like Levaquin) drugs or for patients with fluoroquinolone side effects. All of these commonly used drugs can take people on a bad ride with chronic pain. I haven't taken either of these medications, but it thought it may help to know that the symptoms you experienced are common, so the discontinuation of Plaquenil could indeed improve these areas. That buildup can eventually cause the arteries to narrow or harden. 2006. Because the opioids turn your natural pain relieving system off, your body is left without enough chemicals in the system as the drug wears off every four to six hours. **Several types of drugs are linked to the development of myositis in some people 2. If mild it may cause no symptoms. Medications used to lower thyroid hormones, such as methimazole and propylthiouracil also can cause muscle weakness and wasting. Symptoms of muscle weakness include difficulty rising from a chair, brushing your hair, lifting an object off a high shelf, or dropping things. Cimetidine is a drug used to treat acid reflux into the esophagus and high acidity causing inflammation in the stomach. Nevertheless, other causes of upper arm muscle pain, such as shoulder injuries, nerve compression or medical conditions consisting of cancer, stroke or heart attack, may not be immediately evident. Muscle pain due to injury or overuse is most commonly localized to one area. Muscle weakness and severe muscle aches throughout the body can be symptoms of statin-induced rhabdomyolysis, a rapid breakdown of skeletal muscle that causes muscle fibers to be released into the bloodstream. A binge on cocaine can also cause muscle tissue to break down. Opioids (hydrocodone, hydromorphone, oxycodone, morphine): Yes, the drugs used to treat pain can also cause pain. Muscle strains, soreness, pulls or tears are anything from a simple overstretching of a muscle all the way to a complete tear. Cholesterol Drugs. Imagine living in pain for years only to find out that one of your medications is the reason that you are in pain. Likewise, antiparasitics are drugs that treat parasites. Immune scavenger cells (green) crowd around muscle fibers (red), damaging them and causing muscle pain and weakness. The following are the three most common forms of statin-related muscle pain: 1. Inflammation contributes to these symptoms, technically making this a form of myositis. 3. If you have persisting muscle weakness, particularly if it severe, localised, painful or present for more than two to three weeks, you should visit your doctor. In very rare cases, statins may cause liver problems or a potentially life-threatening breakdown in muscle cells. Muscle damage and (leg) pain being just 2 examples. A continuum of muscle problems The clearest risk from statins is muscle damage resulting in weakness, tenderness, or pain.   Coping strategies for easing muscle pain, regardless of the cause, may be useful in the meantime: massage, warm baths, and gentle exercise, for example. Chemotherapy agents used to treat cancer may cause muscle problems and can also lower blood counts 2. Muscle weakness is rarely the only sign of serious underlying disease. Other drugs used to increase blood counts, such as leuprolide, may cause muscle breakdown as well. Myositis: Myositis, a type of myopathy, causes muscle pain and inflammation, as well as an elevation in CK (a muscle enzyme) levels in the blood. Heart Drugs. "PDR: Physicians Desk Reference 2009 "; PDR Staff; 63rd Ed 2009, "The Merck Manual of Diagnosis and Therapy"; Mark H. Beers et al; 18th Ed. Amiodarone is a very effective drug for treating irregular heart rhythms, but has several side effects in some people, including lung disease, causing an overactive or under-active thyroid, discoloration of the skin, vision changes, liver damage and muscle wasting. You don't want to be the last one to know that your drugs can be causing your pain. She is physiatrist in Grass Valley, California. A binge on cocaine can also cause muscle tissue to break down. Feeling tired and suffering from weak muscles is quite often an early sign of a cold or the flu. You might be unaware that your pain could be related to these medications that are under your control. Opioids (hydrocodone, hydromorphone, oxycodone, morphine): Yes, the drugs used to treat pain can also cause pain. These symptoms commonly occur in large muscles in the legs, chest, upper arms, shoulders, or lower back, but can occur elsewhere. According to research recently published in the Journal of the American College of Cardiology, this class of drugs affects the … It might cause drooping of an eyelid or difficulty smiling, depending on … Where ever there is pain, a medication could be the root cause of it. For instance, spinal stenosis can cause leg pain when walking that is hard to distinguish from muscle pain … This leads to gradual muscle weakness and fatigue. Statin-related muscle inflammation and damage occur on a continuum. It is great that you have responded so well to the new medication. 2. Diseases of the neuromuscular system, injuries, metabolic diseases, and toxins can all cause of measurable muscle weakness. Antivirals such as zidovudine and lamivudine used to treat HIV are offenders, as are antiparasitics such as chloroquine used to treat malaria. The next three medications that can cause pain are only available with a prescription, but that does not necessarily mean that your doctor would realize that your pain could be related to one of these drugs. Antibiotics typically refers to drugs that treat bacterial infections, and antivirals are medications that treat viral infections. See your doctor for a pre… Systemic muscle pain — pain throughout your whole body — is more often the result of an infection, an illness or a side effect of a medication. This guide will deal with true weakness, meaning reduced power in the muscles. Fortunately, most cases of muscle weakness which lack obvious cause are reversible. There are different influenza viruses which are highly contagious, and can spread quickly among all manner of people. Dr. Matthew Fox graduated from the University of California with a Bachelor of Arts in molecular, cell and developmental biology and received a M.D. Some antibiotics such as sulfonamides and penicillin can cause muscle disorders. Drugs used to lower cholesterol can cause muscle aching, weakness and breakdown. Medications used to lower thyroid hormones, such as methimazole and propylthiouracil also can cause muscle weakness and wasting. Repetitive motion injuries can cause numbness, tingling, and weakness in a hand, arm, leg, or foot. Carvedilol is used to treat patients with high blood pressure and in cases of heart failure where the heart cannot adequately pump blood to the body. Lithium is a form mood-stabilizing bipolar medication that can cause pain in the joints and muscles, according to the National Institute of Mental Health 2. This author has been verfied for credibility and expertise. Your medications is the reason that you are on.2 are often other signs that give away cause. 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